I don't see why not, but to be honest, I'd be rather annoyed to see a RDM trying to do so. It probably wouldn't die all that quickly.
You're gonna want help for Tristitia anyway unless you brew it, so you might as well bring at least one other person and go for multiple pops.
Also, yeah, it does hit kinda hard, but this is speaking from the perspective of a typical unguarded melee. A prepared RDM could possibly chop down the severity of the hits enough to the point a melee-fight *might* be manageable. Also, if you see it hitting quickly it probably cast Haste on itself. It can be slowed, and Haste-blocked with Slow II. :D Paralyze also works.
Edited, Apr 7th 2011 10:27pm by Fynlar